Scanning Ion Conductance Microscope
Scanning ion conductance microscope using an electrolyte-filled capillary as sensor. Alexander Wolf-Reber, Thesis 2002.
Goal of Thesis
Goal was to build a scanning ion conductance microscope for observing ion current fluctuations in etched ion channels. The microscope uses a micropipette for localizing etched channels in its scanning mode and dock its pipette to the entry of a selected pore in its patch-clamp mode.
Step-and-repeat process of localizing a pore and measure its fluctuation characteristic.
This work was stimulated by Yuri Korchev, Imperial College London, GB.
More (in German).