Ion Track Technology

PhysicsConsult

Reimar Spohr

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Rectification and voltage gating of ion currents in a nanofabricated pore. Z. Siwy, Y. Gu, H.A. Spohr, D. Baur, A. Wolf-Reber, R. Spohr, P. Apel, Y.E. Korchev. Europhysics Letters, v 60, n 3, 1 Nov. 2002, 349-55

We have fabricated a voltage sensor in the form of a conically shaped nanopore in a polyethylene terephthalate (PET) foil. The pore is produced by irradiation of the foil with a single heavy ion and subsequent etching in alkaline solution. The resulting pore functions as a voltage gate and rectifies ion current due to changes of its diameter in an electrical field. Ion currents through the pore show voltage-dependent fluctuations, whose kinetics are similar as in voltage-gated biological ion channels and pores (28 refs.)